Create a cloud instance and a cloud region for Blackblaze using the steps below. Then, create a cloud storage on Backup Exec.
1. Check [Endpoint] after creating a new bucket on Backblaze. (Fig 1).
If the Endpoint is s3.us-west-004.backblazeb2.com, your region is "us-west-004". The endpoint and region are needed to create a cloud instance and a cloud region on Backup Exec Management Command Line Interface.
Fig 1.

2. Ensure to configure [File Versions:] in [Lifecycle Settings] for the Backblaze bucket as [Keep Only Last Version] (Fig 2).
Fig 2.

3. Launch "Backup Exec Management Command Line Interface". Run the commands below to create a cloud instance and a cloud region.
New-BECloudInstance -Name "cloudinstance001" -Provider "Compatible-with-s3-v4" -ServiceHost "s3.us-west-004.backblazeb2.com" -HttpPort "80" -HttpsPort "443" -SslMode “Full” –UrlStyle “Path”
New-BECloudRegion -InstanceName "cloudinstance001" -IsDefaultRegion $true -Name "us-west-004" -Identifier "us-west-004" -ServiceHost "s3.us-west-004.backblazeb2.com"
Note: It is recommended that the Instance Name is created with lowercase, like "cloudinstance001".
4. Launch Backup Exec Admin Console and click [Configure Cloud Storage]. (Fig 3)
Fig 3.

4. Select [S3] and press [Next]. (Fig 4)
Fig 4.

5. Select [cloudinstance001 [compatible-with-s3-v4] ] in [Cloud storage] (Fig 5)
"cloudinstance001" is the name of the cloud instance which was created in step #2.
Fig 5.

6. Click [Add/Edit] button at [Logon account] line and add a logon account for Backblaze. (Fig 5)
Go to Blackblaze web console and get [KeyID] and [ApplicationKey] from the [App keys] tab. (Fig 6)
Specify [KeyID] for the [User Name] of the new logon account. Specify [ApplicationKey] for [Password] and [Confirm password].
After creating the Backblaze logon account, make sure it is selected in [Logon account] (Fig 5)
Fig 6.

7. Buckets appear in [which logical storage unit do you want to use?] screen. Select one and press [Next].
8. Press [Finish].
Cloud Storage is created now. Restart the Backup Exec Services and then use the storage for backups and restores.
Note : Only one Blackblaze bucket is applicable to configure in Backup Exec application due to the limitation from private cloud.